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from Avapro)Jump avapro blood pressure drug navigation, searchIrbesartanSystematic (IUPAC) name2-butyl-3-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4.4]non-1-en-4-oneIdentifiersCAS number 138402-11-6ATC code C09CA04PubChem 3749DrugBank APRD00413Chemical dataFormula C25H28N6OMol. mass 428.53SMILES eMolecules mass.
combination preparations are marketed under similar trade names Aprovel, Karvea, and Avapro.Contents [hide]1 Clinical use1.1 Indications1.2 Combination with diureticIrbesartan is also available in a combination formulation with a low dose thiazide diuretic, invariably hydrochlorothiazide, avapro blood pressure drug achieve an additive antihypertensive effect. Irbesartan/hydrochlorothiazide combination preparations are marketed under similar trade names to avapro blood pressure drug preparations, including CoAprovel, Karvezide, Avalide and Avapro HCT.[edit] avapro blood pressure drug Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, Ritz E, Atkins RC, Rohde R, Raz I; Collaborative Study Group. (2001). "Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes.". N Engl J avapro blood pressure drug 345 (12): 851-60. PMID 11565517.^ Rossi S, avapro blood pressure drug avapro blood pressure drug Medicines avapro blood pressure drug 2006. Adelaide: Australian Medicines Handbook 2006. Adelaide: Australian Medicines Handbook; 2006. ISBN 0-9757919-2-3 IrbesartanFrom.
Hepatic (CYP2C9)Half life 11–15 hoursExcretion Renal 20%, faecal 65%Therapeutic considerationsLicence data EU.
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